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Bryan Johnson's Skincare Protocol: AM & PM Routine

Bryan Johnson's Skincare Protocol: AM & PM Routine

Bryan Johnson's complete skincare protocol for reversing skin aging. When he started Blueprint, his skin was in the 98th percentile for damage with a skin age of 64. Now his skin age has improved to 36. Disclaimer: This guide is for informational purposes only and does not constitute medical advice. Consult with a dermatologist before starting any new skincare routine.

Protocol Steps

1

Get Morning Sunlight (Before 10 AM)

15-30 mins
Get sunlight early in the mornings and later in the afternoons. Avoid direct sun exposure when the UV index is high (10 AM to 4 PM). Early morning sun supports vitamin D production and circadian rhythm without excessive UV damage.
3

Vitamin C Serum (AM)

1 min
Apply vitamin C serum after cleansing. Vitamin C is a potent antioxidant that protects against UV damage, brightens skin, and supports collagen production.
4

Moisturizer (AM & PM)

1 min
Apply moisturizer to lock in hydration and protect the skin barrier. Use a fragrance-free, sensitive-skin formula. Apply morning and evening.
5

Mineral Sunscreen (AM, if going outdoors)

1 min
Apply mineral (zinc oxide) sunscreen SPF 46+ when going outdoors during high UV times. Mineral sunscreen sits on top of skin and reflects UV rays rather than being absorbed. Reapply every 2 hours if in direct sun.
6

Body Exfoliation (2-3x per week)

5 mins
Exfoliate the body 2-3 times per week using a Japanese exfoliating washcloth or African net sponge. This removes dead skin cells and promotes cell turnover.
7

Retinol Serum (PM Only)

1 min
Apply retinol serum in the evening only (retinol increases sun sensitivity). Retinol promotes cell turnover, reduces fine lines, and improves skin texture. Start slowly and build tolerance.
8

OneSkin OS-01 Peptide (AM & PM)

2 mins
Apply OneSkin's OS-01 peptide to face and body. OS-01 is a proprietary peptide shown in studies to reduce biological skin age by targeting senescent cells.

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Products referenced in the protocol, gathered into one checklist.

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CeraVe Hydrating Cleanser

Skincare

CeraVe Hydrating Facial Cleanser, Moisturizing Face Wash For Dry Skin, Hyaluronic Acid + Ceramides + Glycerin, Hydrating Cleanser For Normal To Dry Skin, National Eczema Association Certified

$15.97

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EltaMD UV Daily SPF 40

Skincare

EltaMD UV Daily Face Sunscreen Moisturizer with Zinc Oxide, Daily Face Moisturizer with SPF, Great for Dry, Combination, and Normal Skin

$41.00

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OneSkin FACE & BODY OS-01 Peptide Topical Supplement | Skin Longevity Age Reversal Body Moisturizer & Face Moisturizer

Skincare

$190.00

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Vanicream Facial Cleanser

Skincare

Vanicream Gentle Facial Cleanser with Pump Dispenser - 8 fl oz - Formulated Without Common Irritants for Those with Sensitive Skin

$9.97

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Vanicream Vitamin C Set

Skincare

Vanicream Daily Facial Moisturizer - 3 fl oz Vitamin C Serum - 1.2 Fl Oz

$31.94

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Vanicream Moisturizing Cream

Skincare

Vanicream Moisturizing Skin Cream with Pump Dispenser - 16 fl oz (1 lb) - Moisturizer Formulated Without Common Irritants for Those with Sensitive Skin

$13.43

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RIUOTA Exfoliating Washcloths

Wellness

RIUOTA 3 Pieces Exfoliating Washcloth Shower Towel African Net Sponge Japanese Wash Cloth Face Exfoliating Sponge Loofah Exfoliating Body Scrubber for Body Exfoliation

$6.99

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CeraVe Retinol Serum

Skincare

CeraVe Resurfacing Retinol Serum For Post Acne Marks, Formulated With Licorice Root Extract & Niacinamide, Brightening Serum & Pore Minimizer For Face, Post Acne Skin Barrier Repair, Non-Comedogenic

$18.68

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